Structural insights and molecular dynamics into the inhibitory mechanism of a Kunitz-type trypsin inhibitor from Tamarindus indica L

• Hauptverfasser: Amanda Fernandes de Medeiros (Verfasst von), Beatriz Blenda Pinheiro de Souza (Verfasst von), Lucas Pinheiro Coutinho (Verfasst von), Aline Melro Murad (Verfasst von), Paula Ivani Medeiros dos Santos (Verfasst von), Norberto de Kássio Vieira Monteiro (Verfasst von), Elizeu Antunes dos Santos (Verfasst von), Bruna Leal Lima Maciel (Verfasst von), Ana Heloneida de Araújo Morais (Verfasst von)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Trypsin inhibitors from tamarind seed have been studied in vitro and in preclinical studies for the treatment of obesity, its complications and associated comorbidities. It is still necessary to fully understand the structure and behaviour of these molecules. We purifed this inhibitor, sequenced de...