Botulinum toxin A injection for chronic anal fissures and anal sphincter spasm improves quality of life in recessive dystrophic epidermolysis bullosa

• मुख्य लेखकों: Cassandra Chaptini, MBBS (लेखक), Genevieve Casey, MBBS (लेखक), Adam G. Harris, MBChB (लेखक), David Wattchow, FRACS (लेखक), Lynne Gordon, FACD (लेखक), Dedee F. Murrell, MA, BMBCh, FAAD, MD, FACD, FRCP (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wolters Kluwer, 2015-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

We report a 20-year-old female with generalized, severe, recessive dystrophic epidermolysis bullosa who developed secondary chronic anal fissures. This resulted in anal sphincter spasm and severe, disabling pain. She was treated with five botulinum toxin A injections into the internal anal sphincter...