Premature Stroke Secondary to Severe Hypertension Results from Liddle Syndrome Caused by a Novel SCNN1B Mutation

• Main Authors: Peng Fan (Author), Di Zhang (Author), Xiao-Cheng Pan (Author), Kun-Qi Yang (Author), Qiong-Yu Zhang (Author), Yi-Ting Lu (Author), Ying Zhang (Author), Xue-Ying Liu (Author), Wen-Jun Ma (Author), Hui-Min Zhang (Author), Lei Song (Author), Jun Cai (Author), Ya-Xin Liu (Author), Xian-Liang Zhou (Author)
• Format: Book
• Published: Karger Publishers, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Liddle syndrome (LS), an autosomal dominant and inherited monogenic hypertension syndrome caused by pathogenic mutations in the epithelial sodium channel (ENaC) genes SCNN1A, SCNN1B, and SCNN1G. Objective: This study was designed to identify a novel SCNN1B missense mutation in a Chines...