A Japanese case of castration-resistant prostate cancer with BRCA2 and RB1 co-loss and TP53 mutation: a case report

• 主要な著者: Tomohiro Iwasawa (著者), Takeo Kosaka (著者), Shinya Morita (著者), Shuji Mikami (著者), Kohei Nakamura (著者), Hiroshi Hongo (著者), Hiroshi Nishihara (著者), Mototsugu Oya (著者)
• フォーマット: 図書
• 出版事項: BMC, 2022-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Abnormalities in homologous recombination contribute to the aggressive nature of castration-resistant prostate cancer. Retinoblastoma transcriptional corepressor 1 (RB1) and breast cancer 2 (BRCA2) exist close to each other in the same chromosome, and the significance of their co...