Proliferation of Genetically Modified Human Cells on Electrospun Nanofiber Scaffolds

• Prif Awduron: Mandula Borjigin (Awdur), Bryan Strouse (Awdur), Rohina A Niamat (Awdur), Pawel Bialk (Awdur), Chris Eskridge (Awdur), Jingwei Xie (Awdur), Eric B Kmiec (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2012-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Gene editing is a process by which single base mutations can be corrected, in the context of the chromosome, using single-stranded oligodeoxynucleotides (ssODNs). The survival and proliferation of the corrected cells bearing modified genes, however, are impeded by a phenomenon known as reduced proli...