Tissue Expression of Hypoxia-Inducible Factor 1 Alpha (HIF-1A) in Wilms Tumor
INTRODUCTION: The hypoxia- inducible factor (HIF) is an alpha (α)/ beta (β) heterodimeric DNA binding complex and directs an extensive transcriptional response involving the induction of genes relevant to tumor progression, such as angiogenesis, glucose/ energy metabolism, cellular growth, metastasi...
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