Tissue Expression of Hypoxia-Inducible Factor 1 Alpha (HIF-1A) in Wilms Tumor

• Main Authors: Emel Tekin (Author), Gülden Diniz (Author), Hülya Tosun Yıldırım (Author), Haldun Öniz (Author), Canan Vergin (Author)
• Format: Book
• Published: Galenos Publishing House, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

INTRODUCTION: The hypoxia- inducible factor (HIF) is an alpha (α)/ beta (β) heterodimeric DNA binding complex and directs an extensive transcriptional response involving the induction of genes relevant to tumor progression, such as angiogenesis, glucose/ energy metabolism, cellular growth, metastasi...