Monitoring the hydrolyzation of aspirin during the dissolution testing for aspirin delayed-release tablets with a fiber-optic dissolution system

• Main Authors: Yan Wang (Author), Ping-Ping Xu (Author), Xin-Xia Li (Author), Kun Nie (Author), Ming-Fu Tuo (Author), Bin Kong (Author), Jian Chen (Author)
• Format: Book
• Published: Elsevier, 2012-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this study was to investigate the hydrolyzation of aspirin during the process of dissolution testing for aspirin delayed-release tablets. Hydrolysis product of salicylic acid can result in adverse effects and affect the determination of dissolution rate assaying. In this study, the te...