Monitoring the hydrolyzation of aspirin during the dissolution testing for aspirin delayed-release tablets with a fiber-optic dissolution system

• Egile Nagusiak: Yan Wang (Egilea), Ping-Ping Xu (Egilea), Xin-Xia Li (Egilea), Kun Nie (Egilea), Ming-Fu Tuo (Egilea), Bin Kong (Egilea), Jian Chen (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2012-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The purpose of this study was to investigate the hydrolyzation of aspirin during the process of dissolution testing for aspirin delayed-release tablets. Hydrolysis product of salicylic acid can result in adverse effects and affect the determination of dissolution rate assaying. In this study, the te...