Tyrphostin AG-related compounds attenuate H2O2-induced TRPM2-dependent and -independent cellular responses

Purpose: TRPM2 is a Ca2+-permeable channel that is activated by H2O2. TRPM2-mediated Ca2+ signaling has been implicated in the aggravation of inflammatory diseases. Therefore, the development of TRPM2 inhibitors to prevent the aggravation of these diseases is expected. We recently reported that some...

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Main Authors: Shinichiro Yamamoto (Author), Takahiro Toda (Author), Ryo Yonezawa (Author), Takaharu Negoro (Author), Shunichi Shimizu (Author)
Format: Book
Published: Elsevier, 2017-05-01T00:00:00Z.
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Call Number: A1234.567
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