Tyrphostin AG-related compounds attenuate H2O2-induced TRPM2-dependent and -independent cellular responses
Purpose: TRPM2 is a Ca2+-permeable channel that is activated by H2O2. TRPM2-mediated Ca2+ signaling has been implicated in the aggravation of inflammatory diseases. Therefore, the development of TRPM2 inhibitors to prevent the aggravation of these diseases is expected. We recently reported that some...
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Elsevier,
2017-05-01T00:00:00Z.
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A1234.567 |
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Kopie 1 | Beschikbaar |