Different Responses to Drug Safety Screening Targets between Human Neonatal and Infantile Heart Tissue and Cardiac Bodies Derived from Human-Induced Pluripotent Stem Cells

Aims. Induced pluripotent stem cell-derived cardiomyocytes (iPS-CMs) have become a promising tool in cardiovascular safety pharmacology. Immaturity of iPS-CMs remains an ongoing concern. We compared electrophysiological and contractile features of cardiac bodies (hiPS-CBs) derived from human-induced...

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Hoofdauteurs: Jan Trieschmann (Auteur), Moritz Haustein (Auteur), Annette Köster (Auteur), Jürgen Hescheler (Auteur), Konrad Brockmeier (Auteur), Gerardus Bennink (Auteur), Tobias Hannes (Auteur)
Formaat: Boek
Gepubliceerd in: Hindawi Limited, 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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Plaatsingsnummer: A1234.567
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