Rolipram improves facilitation of contextual fear extinction in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease

• Main Authors: Ken-ichi Kinoshita (Author), Yoshikage Muroi (Author), Toshihiro Unno (Author), Toshiaki Ishii (Author)
• פורמט: ספר
• יצא לאור: Elsevier, 2017-05-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Cognitive impairment often occurs in Parkinson's disease (PD), but the mechanism of onset remains unknown. Recently, we reported that PD model mice produced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) show facilitation of hippocampal memory extinction, which may be the cause of cogni...