Rolipram improves facilitation of contextual fear extinction in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease

• 主要な著者: Ken-ichi Kinoshita (著者), Yoshikage Muroi (著者), Toshihiro Unno (著者), Toshiaki Ishii (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2017-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Cognitive impairment often occurs in Parkinson's disease (PD), but the mechanism of onset remains unknown. Recently, we reported that PD model mice produced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) show facilitation of hippocampal memory extinction, which may be the cause of cogni...