Combining phage display with SMRTbell next-generation sequencing for the rapid discovery of functional scFv fragments

• मुख्य लेखकों: Francesco Nannini (लेखक), Lenart Senicar (लेखक), Farhaan Parekh (लेखक), Khai J. Kong (लेखक), Alexander Kinna (लेखक), Reyisa Bughda (लेखक), James Sillibourne (लेखक), Xihao Hu (लेखक), Biao Ma (लेखक), Yuchen Bai (लेखक), Mathieu Ferrari (लेखक), Martin A. Pule (लेखक), Shimobi C. Onuoha (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Phage display technology in combination with next-generation sequencing (NGS) currently is a state-of-the-art method for the enrichment and isolation of monoclonal antibodies from diverse libraries. However, the current NGS methods employed for sequencing phage display libraries are limited by the s...