Effect of FcRn antagonism on protective antibodies and to vaccines in IgG-mediated autoimmune diseases pemphigus and generalised myasthenia gravis

• প্রধান লেখক: Jeffrey T. Guptill (লেখক), John W. Sleasman (লেখক), Sophie Steeland (লেখক), Magdalena Sips (লেখক), Deborah Gelinas (লেখক), Hans de Haard (লেখক), Antoine Azar (লেখক), Kevin L. Winthrop (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Taylor & Francis Group, 2022-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Antagonism of the neonatal Fc receptor (FcRn) by efgartigimod has been studied in several autoimmune diseases mediated by immunoglobulin G (IgG) as a therapeutic approach to remove pathogenic IgGs. Whereas reduction of pathogenic titres has demonstrated efficacy in multiple autoimmune diseases, redu...