Effect of FcRn antagonism on protective antibodies and to vaccines in IgG-mediated autoimmune diseases pemphigus and generalised myasthenia gravis

• मुख्य लेखकों: Jeffrey T. Guptill (लेखक), John W. Sleasman (लेखक), Sophie Steeland (लेखक), Magdalena Sips (लेखक), Deborah Gelinas (लेखक), Hans de Haard (लेखक), Antoine Azar (लेखक), Kevin L. Winthrop (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2022-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Antagonism of the neonatal Fc receptor (FcRn) by efgartigimod has been studied in several autoimmune diseases mediated by immunoglobulin G (IgG) as a therapeutic approach to remove pathogenic IgGs. Whereas reduction of pathogenic titres has demonstrated efficacy in multiple autoimmune diseases, redu...