Bone marrow transplantation corrects haemolytic anaemia in a novel ENU mutagenesis mouse model of TPI deficiency

In this study, we performed a genome-wide N-ethyl-N-nitrosourea (ENU) mutagenesis screen in mice to identify novel genes or alleles that regulate erythropoiesis. Here, we describe a recessive mouse strain, called RBC19, harbouring a point mutation within the housekeeping gene, Tpi1, which encodes th...

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Main Authors: Ashlee J. Conway (Author), Fiona C. Brown (Author), Elinor J. Hortle (Author), Gaetan Burgio (Author), Simon J. Foote (Author), Craig J. Morton (Author), Stephen M. Jane (Author), David J. Curtis (Author)
Format: Book
Published: The Company of Biologists, 2018-05-01T00:00:00Z.
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3rd Floor Main Library

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