Pharmacogenetic Analysis of Voriconazole Treatment in Children

• Egile Nagusiak: Romy Tilen (Egilea), Paolo Paioni (Egilea), Aljoscha N. Goetschi (Egilea), Roland Goers (Egilea), Isabell Seibert (Egilea), Daniel Müller (Egilea), Julia A. Bielicki (Egilea), Christoph Berger (Egilea), Stefanie D. Krämer (Egilea), Henriette E. Meyer zu Schwabedissen (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Voriconazole is among the first-line antifungal drugs to treat invasive fungal infections in children and known for its pronounced inter- and intraindividual pharmacokinetic variability. Polymorphisms in genes involved in the metabolism and transport of voriconazole are thought to influence serum co...