Pharmacogenetic Analysis of Voriconazole Treatment in Children

• Главные авторы: Romy Tilen (Автор), Paolo Paioni (Автор), Aljoscha N. Goetschi (Автор), Roland Goers (Автор), Isabell Seibert (Автор), Daniel Müller (Автор), Julia A. Bielicki (Автор), Christoph Berger (Автор), Stefanie D. Krämer (Автор), Henriette E. Meyer zu Schwabedissen (Автор)
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• Опубликовано: MDPI AG, 2022-06-01T00:00:00Z.
• Предметы: article
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Voriconazole is among the first-line antifungal drugs to treat invasive fungal infections in children and known for its pronounced inter- and intraindividual pharmacokinetic variability. Polymorphisms in genes involved in the metabolism and transport of voriconazole are thought to influence serum co...