Identifying genes that mediate anthracyline toxicity in immune cells

• Main Authors: Amber eFrick (Author), Oscar Takeo Suzuki (Author), Cristina eBenton (Author), Bethany eParks (Author), Yuri eFedoriw (Author), Kristy eRichards (Author), Russell eThomas (Author), Tim eWiltshire (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The role of the immune system in response to chemotherapeutic agents remains elusive. The interpatient variability observed in immune and chemotherapeutic cytotoxic responses is likely, at least in part, due to complex genetic differences. Through the use of a panel of genetically diverse mouse inbr...