Identifying genes that mediate anthracyline toxicity in immune cells

• Главные авторы: Amber eFrick (Автор), Oscar Takeo Suzuki (Автор), Cristina eBenton (Автор), Bethany eParks (Автор), Yuri eFedoriw (Автор), Kristy eRichards (Автор), Russell eThomas (Автор), Tim eWiltshire (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2015-04-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

The role of the immune system in response to chemotherapeutic agents remains elusive. The interpatient variability observed in immune and chemotherapeutic cytotoxic responses is likely, at least in part, due to complex genetic differences. Through the use of a panel of genetically diverse mouse inbr...