An efficient AAV vector system of Rec2 serotype for intravenous injection to study metabolism in brown adipocytes in vivo

• Autors principals: Janina Behrens (Autor), Ingke Braren (Autor), Michelle Y. Jaeckstein (Autor), Luka Lilie (Autor), Markus Heine (Autor), Finnja Sass (Autor), Judith Sommer (Autor), Dagmar Silbert-Wagner (Autor), Marceline M. Fuh (Autor), Anna Worthmann (Autor), Leon Straub (Autor), Tarek Moustafa (Autor), Joerg Heeren (Autor), Ludger Scheja (Autor)
• Format: Llibre
• Publicat: Elsevier, 2024-10-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Objective: Recombinant adeno-associated virus (rAAV) vectors are powerful tools for the sustained expression of proteins in vivo and have been successfully used for mechanistic studies in mice. A major challenge associated with this method is to obtain tissue specificity and high expression levels w...