Disulfiram Inclusion Complexes - A Nebulization Approach to Fight COVID-19

• Asıl Yazarlar: Ana Maria Pereira (Yazar), Ayse Kaya (Yazar), Dan Alves (Yazar), Niusha Ansari-Fard (Yazar), Mohammad Najlah (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: University of Huddersfield Press, 2022-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Disulfiram (DS) has an excellent anti-viral activity; however, its low water-solubility and first-pass metabolism are limiting its clinical applications. Cyclodextrins (CDs) have been used as solubility enhancers and carriers of DS proposed for inhalation to treat SARS-CoV-19. Two types of CDs (hydr...