The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors
The clinically used antibiotic Furagin and its derivatives possess inhibitory activity on human (h) carbonic anhydrases (CA, EC 4.2.1.1), some of which are highly expressed in various tissues and malignancies (hCA IX/XII). Furagin exhibited good hCA IX and XII inhibition with KIs of 260 and 57 nM, r...
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Main Authors: | , , , , , , |
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Format: | Book |
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Taylor & Francis Group,
2020-01-01T00:00:00Z.
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Connect to this object online.3rd Floor Main Library
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A1234.567 |
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Copy 1 | Available |