CRISPR/Cas9-Mediated Treatment Ameliorates the Phenotype of the Epidermolytic Palmoplantar Keratoderma-like Mouse
CRISPR/Cas9 has been confirmed as a distinctly efficient, simple-to-configure, highly specific genome-editing tool that has been used to treat monogenetic disorders. Epidermolytic palmoplantar keratoderma (EPPK) is a common autosomal dominant keratin disease resulting from dominant-negative mutation...
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Main Authors: | Xiao-Rui Luan (Author), Xiao-Ling Chen (Author), Yue-Xiao Tang (Author), Jin-Yan Zhang (Author), Xiang Gao (Author), Hai-Ping Ke (Author), Zhao-Yu Lin (Author), Xian-Ning Zhang (Author) |
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Format: | Book |
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Elsevier,
2018-09-01T00:00:00Z.
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