Soluble receptors for advanced glycation end-products prevent unilateral ureteral obstruction-induced renal fibrosis

• Main Authors: Chan Ho Kim (Author), Hye-Young Kang (Author), Gyuri Kim (Author), Jimin Park (Author), Bo Young Nam (Author), Jung Tak Park (Author), Seung Hyeok Han (Author), Shin-Wook Kang (Author), Tae-Hyun Yoo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: The receptor for advanced glycation end products (RAGE) and its ligands, such as high-mobility group protein box 1 (HMGB1), play an important role in the accumulation of extracellular matrix in chronic kidney diseases with tubulointerstitial fibrosis. Blocking RAGE signaling with solub...