Soluble receptors for advanced glycation end-products prevent unilateral ureteral obstruction-induced renal fibrosis

• Auteurs principaux: Chan Ho Kim (Auteur), Hye-Young Kang (Auteur), Gyuri Kim (Auteur), Jimin Park (Auteur), Bo Young Nam (Auteur), Jung Tak Park (Auteur), Seung Hyeok Han (Auteur), Shin-Wook Kang (Auteur), Tae-Hyun Yoo (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Introduction: The receptor for advanced glycation end products (RAGE) and its ligands, such as high-mobility group protein box 1 (HMGB1), play an important role in the accumulation of extracellular matrix in chronic kidney diseases with tubulointerstitial fibrosis. Blocking RAGE signaling with solub...