Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations

Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations

Sulphamate and sulphamide derivatives have been largely investigated as carbonic anhydrase inhibitors (CAIs) by means of different experimental techniques. However, the structural determinants responsible for their different binding mode to the enzyme active site were not clearly defined so far. In...

Full description

Saved in:
Bibliographic Details
Main Authors: Giuseppina De Simone (Author), Emma Langella (Author), Davide Esposito (Author), Claudiu T. Supuran (Author), Simona Maria Monti (Author), Jean-Yves Winum (Author), Vincenzo Alterio (Author)
Format: Book
Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available

Similar Items