Combined Treatment with Acalabrutinib and Rapamycin Inhibits Glioma Stem Cells and Promotes Vascular Normalization by Downregulating BTK/mTOR/VEGF Signaling
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults, with a median duration of survival of approximately 14 months after diagnosis. High resistance to chemotherapy remains a major problem. Previously, BTK has been shown to be involved in the intracellular signal transductio...
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Main Authors: | Yu-Kai Su (Author), Oluwaseun Adebayo Bamodu (Author), I-Chang Su (Author), Narpati Wesa Pikatan (Author), Iat-Hang Fong (Author), Wei-Hwa Lee (Author), Chi-Tai Yeh (Author), Hsiao-Yean Chiu (Author), Chien-Min Lin (Author) |
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Format: | Book |
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MDPI AG,
2021-08-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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