Development and characterization of injectable depot forming thermoresponsive hydrogel for the sustained intrascleral delivery of Sunitinib

• Main Authors: Shilpkala Gade (Author), Eneko Larrañeta (Author), Ryan F Donnelly (Author), Rocio Herrero Vanrell (Author), Carmen Isabel Alvarez Lorenzo (Author), Raghu Raj Singh Thakur (Author)
• Format: Book
• Published: University of Huddersfield Press, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Age-related macular degeneration (AMD) is a potentially blinding posterior segment disease; inflammatory responses and subretinal drusen formation lead to leaky blood vessels. The current treatment method involves intravitreal injections of anti-VEGF agents, which is highly invasive and requires fre...