Development and characterization of injectable depot forming thermoresponsive hydrogel for the sustained intrascleral delivery of Sunitinib

• Auteurs principaux: Shilpkala Gade (Auteur), Eneko Larrañeta (Auteur), Ryan F Donnelly (Auteur), Rocio Herrero Vanrell (Auteur), Carmen Isabel Alvarez Lorenzo (Auteur), Raghu Raj Singh Thakur (Auteur)
• Format: Livre
• Publié: University of Huddersfield Press, 2022-11-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Age-related macular degeneration (AMD) is a potentially blinding posterior segment disease; inflammatory responses and subretinal drusen formation lead to leaky blood vessels. The current treatment method involves intravitreal injections of anti-VEGF agents, which is highly invasive and requires fre...