Development and characterization of injectable depot forming thermoresponsive hydrogel for the sustained intrascleral delivery of Sunitinib

• Principais autores: Shilpkala Gade (Autor), Eneko Larrañeta (Autor), Ryan F Donnelly (Autor), Rocio Herrero Vanrell (Autor), Carmen Isabel Alvarez Lorenzo (Autor), Raghu Raj Singh Thakur (Autor)
• Formato: Livro
• Publicado em: University of Huddersfield Press, 2022-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Age-related macular degeneration (AMD) is a potentially blinding posterior segment disease; inflammatory responses and subretinal drusen formation lead to leaky blood vessels. The current treatment method involves intravitreal injections of anti-VEGF agents, which is highly invasive and requires fre...