Methanethiosulfonate derivatives as ligands of the STAT3-SH2 domain
With the aim to discover new STAT3 direct inhibitors, potentially useful as anticancer agents, a set of methanethiosulfonate drug hybrids were synthesized. The in vitro tests showed that all the thiosulfonic compounds were able to strongly and selectively bind STAT3-SH2 domain, whereas the parent dr...
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| Autores principales: | , , , , , |
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| Formato: | Libro |
| Publicado: |
Taylor & Francis Group,
2017-01-01T00:00:00Z.
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| Acceso en línea: | Connect to this object online. |
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| Número de Clasificación: |
A1234.567 |
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| Copia 1 | Disponible |