Therapeutic strategies for the costimulatory molecule OX40 in T-cell-mediated immunity

The T cell co-stimulatory molecule OX40 and its cognate ligand OX40L have attracted broad research interest as a therapeutic target in T cell-mediated diseases. Accumulating preclinical evidence highlights the therapeutic efficacy of both agonist and blockade of the OX40-OX40L interaction. Despite t...

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Autores principales: Yu Fu (Autor), Qing Lin (Autor), Zhirong Zhang (Autor), Ling Zhang (Autor)
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Publicado: Elsevier, 2020-03-01T00:00:00Z.
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