Therapeutic strategies for the costimulatory molecule OX40 in T-cell-mediated immunity

• প্রধান লেখক: Yu Fu (লেখক), Qing Lin (লেখক), Zhirong Zhang (লেখক), Ling Zhang (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2020-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The T cell co-stimulatory molecule OX40 and its cognate ligand OX40L have attracted broad research interest as a therapeutic target in T cell-mediated diseases. Accumulating preclinical evidence highlights the therapeutic efficacy of both agonist and blockade of the OX40-OX40L interaction. Despite t...