Morphological predictors for microsatellite instability in urothelial carcinoma

• Main Authors: Eduardo Sobrino-Reig (Author), Telma Meizoso (Author), Jesús García (Author), David Varillas-Delgado (Author), Yasmina B. Martin (Author)
• Format: Book
• Published: BMC, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Introduction Microsatellite instability occurs due to a series of mutations in the DNA pairing error repair (Mismatch repair; MMR) genes, which can affect germ cells as occurs in Lynch syndrome, whose patients are at high risk of developing multiple cancers. The loss of MMR protein is commo...