Morphological predictors for microsatellite instability in urothelial carcinoma

• Päätekijät: Eduardo Sobrino-Reig (Tekijä), Telma Meizoso (Tekijä), Jesús García (Tekijä), David Varillas-Delgado (Tekijä), Yasmina B. Martin (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2021-11-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Introduction Microsatellite instability occurs due to a series of mutations in the DNA pairing error repair (Mismatch repair; MMR) genes, which can affect germ cells as occurs in Lynch syndrome, whose patients are at high risk of developing multiple cancers. The loss of MMR protein is commo...