Morphological predictors for microsatellite instability in urothelial carcinoma

• Hlavní autoři: Eduardo Sobrino-Reig (Autor), Telma Meizoso (Autor), Jesús García (Autor), David Varillas-Delgado (Autor), Yasmina B. Martin (Autor)
• Médium: Kniha
• Vydáno: BMC, 2021-11-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Abstract Introduction Microsatellite instability occurs due to a series of mutations in the DNA pairing error repair (Mismatch repair; MMR) genes, which can affect germ cells as occurs in Lynch syndrome, whose patients are at high risk of developing multiple cancers. The loss of MMR protein is commo...