Morphological predictors for microsatellite instability in urothelial carcinoma

• Hoofdauteurs: Eduardo Sobrino-Reig (Auteur), Telma Meizoso (Auteur), Jesús García (Auteur), David Varillas-Delgado (Auteur), Yasmina B. Martin (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2021-11-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Introduction Microsatellite instability occurs due to a series of mutations in the DNA pairing error repair (Mismatch repair; MMR) genes, which can affect germ cells as occurs in Lynch syndrome, whose patients are at high risk of developing multiple cancers. The loss of MMR protein is commo...