Tanshinol Alleviates Microcirculation Disturbance and Impaired Bone Formation by Attenuating TXNIP Signaling in GIO Rats

• Κύριοι συγγραφείς: Wenxiu Lai (Συγγραφέας), Yulin Mo (Συγγραφέας), Dongtao Wang (Συγγραφέας), Ying Zhong (Συγγραφέας), Lujiao Lu (Συγγραφέας), Jiajia Wang (Συγγραφέας), Liao Cui (Συγγραφέας), Yanzhi Liu (Συγγραφέας), Yajun Yang (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Impaired bone formation is the main characteristics of glucocorticoid (GC)-induced osteoporosis (GIO), which can be ameliorated by tanshinol, an aqueous polyphenol isolated from Salvia miltiorrhiza Bunge. However, the underlying mechanism is still not entirely clear. In the present study, we determi...