Therapeutic Dose Response of Acoustic Cluster Therapy in Combination With Irinotecan for the Treatment of Human Colon Cancer in Mice

• Auteurs principaux: Nigel Bush (Auteur), Andrew Healey (Auteur), Anant Shah (Auteur), Gary Box (Auteur), Vladimir Kirkin (Auteur), Spiros Kotopoulis (Auteur), Svein Kvåle (Auteur), Per Christian Sontum (Auteur), Jeffrey Bamber (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2019-11-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Introduction: Acoustic Cluster Therapy (ACT) comprises coadministration of a formulation containing microbubble-microdroplet clusters (PS101) together with a regular medicinal drug and local ultrasound (US) insonation of the targeted pathological tissue. PS101 is confined to the vascular compartment...