Mutation analysis of the TUBB8 gene in primary infertile women with oocyte maturation arrest

Abstract Background Oocyte maturation arrest at metaphase I leads to fertilization failure in humans. In early embryos, the tubulin beta 8 class VIII (TUBB8) encodes a β-tubulin isotype and aids in the assembling of the human oocyte spindle. Mutations in the TUBB8 potentially interfere with human oo...

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Main Authors: Zhongyuan Yao (Author), Jun Zeng (Author), Huimin Zhu (Author), Jing Zhao (Author), Xiaoxia Wang (Author), Qiuping Xia (Author), Yanping Li (Author), Lingqian Wu (Author)
Format: Book
Published: BMC, 2022-03-01T00:00:00Z.
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3rd Floor Main Library

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