Mutation analysis of the TUBB8 gene in primary infertile women with oocyte maturation arrest

• Hoofdauteurs: Zhongyuan Yao (Auteur), Jun Zeng (Auteur), Huimin Zhu (Auteur), Jing Zhao (Auteur), Xiaoxia Wang (Auteur), Qiuping Xia (Auteur), Yanping Li (Auteur), Lingqian Wu (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2022-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background Oocyte maturation arrest at metaphase I leads to fertilization failure in humans. In early embryos, the tubulin beta 8 class VIII (TUBB8) encodes a β-tubulin isotype and aids in the assembling of the human oocyte spindle. Mutations in the TUBB8 potentially interfere with human oo...