Mutation analysis of the TUBB8 gene in primary infertile women with oocyte maturation arrest

• मुख्य लेखकों: Zhongyuan Yao (लेखक), Jun Zeng (लेखक), Huimin Zhu (लेखक), Jing Zhao (लेखक), Xiaoxia Wang (लेखक), Qiuping Xia (लेखक), Yanping Li (लेखक), Lingqian Wu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2022-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Oocyte maturation arrest at metaphase I leads to fertilization failure in humans. In early embryos, the tubulin beta 8 class VIII (TUBB8) encodes a β-tubulin isotype and aids in the assembling of the human oocyte spindle. Mutations in the TUBB8 potentially interfere with human oo...