Mutation analysis of the TUBB8 gene in primary infertile women with oocyte maturation arrest
Abstract Background Oocyte maturation arrest at metaphase I leads to fertilization failure in humans. In early embryos, the tubulin beta 8 class VIII (TUBB8) encodes a β-tubulin isotype and aids in the assembling of the human oocyte spindle. Mutations in the TUBB8 potentially interfere with human oo...
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2022-03-01T00:00:00Z.
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