Oral Efficacy of Apigenin against Cutaneous Leishmaniasis: Involvement of Reactive Oxygen Species and Autophagy as a Mechanism of Action.

• Asıl Yazarlar: Fernanda Fonseca-Silva (Yazar), Job D F Inacio (Yazar), Marilene M Canto-Cavalheiro (Yazar), Rubem F S Menna-Barreto (Yazar), Elmo E Almeida-Amaral (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2016-02-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The treatment for leishmaniasis is currently based on pentavalent antimonials and amphotericin B; however, these drugs result in numerous adverse side effects. The lack of affordable therapy has necessitated the urgent development of new drugs that are efficacious, safe, and more accessible to patie...