Hydroxyzine, a First Generation H1-Receptor Antagonist, Inhibits Human Ether-a-go-go-Related Gene (HERG) Current and Causes Syncope in a Patient With the HERG Mutation

• मुख्य लेखकों: Tomoko Sakaguchi (लेखक), Hideki Itoh (लेखक), Wei-Guang Ding (लेखक), Keiko Tsuji (लेखक), Iori Nagaoka (लेखक), Yuko Oka (लेखक), Takashi Ashihara (लेखक), Makoto Ito (लेखक), Yoshihiro Yumoto (लेखक), Naoko Zenda (लेखक), Yukei Higashi (लेखक), Youichi Takeyama (लेखक), Hiroshi Matsuura (लेखक), Minoru Horie (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2008-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

QT prolongation, a risk factor for arrhythmias, can result from genetic variants in one (or more) of the genes governing cardiac repolarization as well as intake of drugs known to affect a cardiac K+ channel encoded by human ether-a-go-go-related gene (HERG). In this paper, we will report a case of...