Intradermal delivery of vaccines: potential benefits and current challenges

• Главные авторы: JK Hickling (Автор), KR Jones (Автор), M Friede (Автор), D Zehrung (Автор), D Chen (Автор), D Kristensen (Автор)
• Формат: ‌
• Опубликовано: The World Health Organization, 2011-03-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Delivery of vaccine antigens to the dermis and/or epidermis of human skin (i.e. intradermal delivery) might be more efficient than injection into the muscle or subcutaneous tissue, thereby reducing the volumes of antigen. This is known as dose-sparing and has been demonstrated in clinical trials wit...