Increased plasmablasts enhance T cell-mediated beta cell destruction and promote the development of type 1 diabetes

Abstract Background Although type 1 diabetes (T1D) is typically described as a T cell-mediated autoimmune disease, increasing evidence for a role of B cells has emerged. However, the pivotal disease-relevant B cell subset and its contribution to islet autoimmunity remain elusive. Methods The frequen...

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Main Authors: Qing Ling (Author), Lei Shen (Author), Wei Zhang (Author), DuoDuo Qu (Author), Hongdong Wang (Author), Bin Wang (Author), Yong Liu (Author), Jing Lu (Author), Dalong Zhu (Author), Yan Bi (Author)
Format: Book
Published: BMC, 2022-02-01T00:00:00Z.
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