Increased plasmablasts enhance T cell-mediated beta cell destruction and promote the development of type 1 diabetes
Abstract Background Although type 1 diabetes (T1D) is typically described as a T cell-mediated autoimmune disease, increasing evidence for a role of B cells has emerged. However, the pivotal disease-relevant B cell subset and its contribution to islet autoimmunity remain elusive. Methods The frequen...
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Main Authors: | , , , , , , , , , |
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Format: | Book |
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BMC,
2022-02-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |