High-Mobility Group Box-1 Induces Decreased Brain-Derived Neurotrophic Factor-Mediated Neuroprotection in the Diabetic Retina

• मुख्य लेखकों: Ahmed M. Abu El-Asrar (लेखक), Mohd Imtiaz Nawaz (लेखक), Mohammad Mairaj Siddiquei (लेखक), Abdullah S. Al-Kharashi (लेखक), Dustan Kangave (लेखक), Ghulam Mohammad (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2013-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

To test the hypothesis that brain-derived neurotrophic factor-(BDNF-) mediated neuroprotection is reduced by high-mobility group box-1 (HMGB1) in diabetic retina, paired vitreous and serum samples from 46 proliferative diabetic retinopathy and 34 nondiabetic patients were assayed for BDNF, HMGB1, so...