Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect
A new series of quinoline derivatives of combretastatin A-4 have been designed, synthesised and demonstrated as tubulin polymerisation inhibitors. These novel compounds showed significant antiproliferative activities, among them, 12c exhibited the most potent inhibitory activity against different ca...
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Główni autorzy: | , , , , , , , , |
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Format: | Książka |
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Taylor & Francis Group,
2021-01-01T00:00:00Z.
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Internet
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A1234.567 |
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Egzemplarz 1 | Dostępne |