Super-resolution imaging for in situ monitoring sub-cellular micro-dynamics of small molecule drug

• Main Authors: Huimin Chen (Author), Guiqian Fang (Author), Youxiao Ren (Author), Weiwei Zou (Author), Kang Ying (Author), Zhiwei Yang (Author), Qixin Chen (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Small molecule drugs play a pivotal role in the arsenal of anticancer pharmacological agents. Nonetheless, their small size poses a challenge when directly visualizing their localization, distribution, mechanism of action (MOA), and target engagement at the subcellular level in real time. We propose...