Super-resolution imaging for in situ monitoring sub-cellular micro-dynamics of small molecule drug

• मुख्य लेखकों: Huimin Chen (लेखक), Guiqian Fang (लेखक), Youxiao Ren (लेखक), Weiwei Zou (लेखक), Kang Ying (लेखक), Zhiwei Yang (लेखक), Qixin Chen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2024-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Small molecule drugs play a pivotal role in the arsenal of anticancer pharmacological agents. Nonetheless, their small size poses a challenge when directly visualizing their localization, distribution, mechanism of action (MOA), and target engagement at the subcellular level in real time. We propose...