Super-resolution imaging for in situ monitoring sub-cellular micro-dynamics of small molecule drug

• Egile Nagusiak: Huimin Chen (Egilea), Guiqian Fang (Egilea), Youxiao Ren (Egilea), Weiwei Zou (Egilea), Kang Ying (Egilea), Zhiwei Yang (Egilea), Qixin Chen (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2024-04-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Small molecule drugs play a pivotal role in the arsenal of anticancer pharmacological agents. Nonetheless, their small size poses a challenge when directly visualizing their localization, distribution, mechanism of action (MOA), and target engagement at the subcellular level in real time. We propose...