Successful Application of Alpha Lipoic Acid Niosomal Formulation in Cerebral Ischemic Reperfusion Injury in Rat Model

• Päätekijät: Mohammad Amin Raeisi Estabragh (Tekijä), Abbas Pardakhty (Tekijä), Saeid Ahmadzadeh (Tekijä), Shahriar Dabiri (Tekijä), Reza Malekpour Afshar (Tekijä), Mohammad Farajli Abbasi (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Tabriz University of Medical Sciences, 2022-05-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Purpose: Free radicals such as hydroxyl and peroxide are contributing factors to neuronaldestruction in cerebral ischemia. Alpha-lipoic acid (ALA) is one of the potent knownantioxidants. Preparation of ALA niosomes allows IV injection and can increase bioavailabilityand penetration into the central...