Successful Application of Alpha Lipoic Acid Niosomal Formulation in Cerebral Ischemic Reperfusion Injury in Rat Model

• Glavni autori: Mohammad Amin Raeisi Estabragh (Autor), Abbas Pardakhty (Autor), Saeid Ahmadzadeh (Autor), Shahriar Dabiri (Autor), Reza Malekpour Afshar (Autor), Mohammad Farajli Abbasi (Autor)
• Format: Knjiga
• Izdano: Tabriz University of Medical Sciences, 2022-05-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Purpose: Free radicals such as hydroxyl and peroxide are contributing factors to neuronaldestruction in cerebral ischemia. Alpha-lipoic acid (ALA) is one of the potent knownantioxidants. Preparation of ALA niosomes allows IV injection and can increase bioavailabilityand penetration into the central...